Roles of the mitochondrial genetics in cancer metastasis: not to be ignored any longer

Small proteins can no longer be ignored.

Small proteins, here defined as proteins of 50 amino acids or fewer in the absence of processing, have traditionally been overlooked due to challenges in their annotation and biochemical detection. In the past several years, however, increasing numbers of small proteins have been identified either through the realization that mutations in intergenic regions are actually within unannotated small...

MRS Shimming: An Important Point Which Should not be Ignored

Introduction: Proton magnetic resonance spectroscopy (MRS) is a well-known device for analyzing the biological fluids metabolically. Obtaining accurate and reliable information via MRS needs a homogeneous magnetic field in order to provide well-defined peaks and uniform water suppression. There are lots of reasons which can disturb the magnetic field homogeneity which can be corrected by a proc...

Roles of Renin-Angiotensin System in the Regulation of Prostate Cancer Bone Metastasis: A Critical Review

Mestastatic prostate cancer cells (MPCCs) frequently metastasize to bone, which is a “favorite soil” for colonization and proliferation of MPCCs. Prostate cancer bone mestastasis is tightly associated with tumor-induced bone lesions, most commonly caused from the etiological imbalance between osteoblastic bone formation and osteoclastic bone resorption, and from the anti-tumor immune response. ...

Underreported, underacknowledged: child abuse can no longer be ignored.

Child abuse is a serious problem in Hong Kong, and the recent Tin Shui Wai tragedy and assault of a 7-year-old boy have caused considerable public concern. Over the past 5 years, the number of new child abuse cases reported to the Child Protection Registry (CPR) by the Social Welfare Department has been increasing, and has recently risen by more than 50% from 622 cases in 2004 to 406 cases in j...

Consultations do not have to be longer.